This fast track antibody is not yet fully characterized. It is subject to these terms and conditions


  • Product nameAnti-Apc1 antibody
    See all Apc1 primary antibodies
  • Description
    Rabbit polyclonal to Apc1

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • SpecificityThis affinity purified antibody is directed against human APC1 at the S355 residue. This antibody is pan reactive for both phosphorylated and non-phosphorylated APC1 at the S355 residue.
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide: SRAHSpPALG conjugated to KLH, corresponding to amino acids 351-359 of Human Apc1.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.01% Sodium Azide
    Constituents: 0.15M Sodium Chloride, 0.02M Potassium Phosphate. pH 7.2
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesThe product was affinity purified from monospecific antiserum by immunoaffinity purification. Antiserum was purified against the non-phosphorylated form of the immunizing peptide.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


  • Application notespeptide ELISA: 1/80000 (determined against 0.1 µg of the phosphorylated and non-phosphorylated forms of the immunizing peptide). Approximately equivalent staining is seen when both the phosphorylated and non-phosphorylated form of the immunizing peptide are bound to the ELISA plate.

    We have tested this antibody on various human tissue lysates and have as yet detected no bands of the appropriate size, however we have seen low background.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionComponent of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
    • PathwayProtein modification; protein ubiquitination.
    • Sequence similaritiesBelongs to the APC1 family.
      Contains 4 PC repeats.
    • Post-translational
      Phosphorylated. Phosphorylation on Ser-355 occurs specifically during mitosis.
    • Information by UniProt
    • Database links
    • Alternative names
      • ANAPC 1 antibody
      • Anapc1 antibody
      • Anaphase promoting complex subunit 1 antibody
      • anaphase-promoting complex 1 (meiotic checkpoint regulator) antibody
      • Anaphase-promoting complex subunit 1 antibody
      • Apc 1 antibody
      • APC1 antibody
      • APC1_HUMAN antibody
      • Cyclosome subunit 1 antibody
      • MCPR antibody
      • Meiotic checkpoint regulator antibody
      • Mitotic checkpoint regulator antibody
      • Protein Tsg 24 antibody
      • Protein Tsg24 antibody
      • Testis-specific gene 24 protein antibody
      • TSG 24 antibody
      • TSG24 antibody
      see all

    References for Anti-Apc1 antibody (ab14207)

    ab14207 has not yet been referenced specifically in any publications.

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