Overview

  • Product nameAnti-Apc10 antibody
    See all Apc10 primary antibodies
  • Description
    Rabbit polyclonal to Apc10
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Synthetic peptide (

    GADPKQLERTG

    ) corresponding to N terminal amino acids 10-20 of Human Apc10.

  • Positive control
    • Human pancreas tissue

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 0.27% Potassium phosphate, 0.88% Sodium chloride
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab117113 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 21 kDa.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionComponent of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesBelongs to the APC10 family.
    Contains 1 DOC domain.
  • Information by UniProt
  • Database links
  • FormIt localises to Cytosol and nucleoplasm.
  • Alternative names
    • ANAPC 10 antibody
    • anapc10 antibody
    • Anaphase promoting complex 10 antibody
    • Anaphase promoting complex subunit 10 antibody
    • Anaphase-promoting complex subunit 10 antibody
    • Apc 10 antibody
    • APC10 antibody
    • APC10_HUMAN antibody
    • Cyclosome subunit 10 antibody
    • DKFZP564L0562 antibody
    • Doc 1 antibody
    • Doc1 antibody
    • Doc1, S. cerevisiae, homolog of antibody
    • OTTHUMP00000220297 antibody
    • OTTHUMP00000220298 antibody
    • OTTHUMP00000220299 antibody
    • OTTHUMP00000220300 antibody
    • OTTHUMP00000220303 antibody
    see all

Anti-Apc10 antibody images

  • ab117113 at 2.5 µg/ml staining Apc10 in Formalin-Fixed, Paraffin-Embedded Human pancreas tissue by Immunohistochemistry.

References for Anti-Apc10 antibody (ab117113)

ab117113 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"