Overview

  • Product name
    Anti-Apc4 antibody [CIV1.1]
    See all Apc4 primary antibodies
  • Description
    Mouse monoclonal [CIV1.1] to Apc4
  • Specificity
    This antibody may be used for the affinity purification of the Anaphase Promoticing Complex (APC/C) by peptide elution.
  • Tested applications
    Suitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human), C terminus.

  • Epitope
    CIVIKVEKLDPELDS
  • Positive control
    • Purified APC/C by silver and mass spectrometr

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    IgG fraction
  • Clonality
    Monoclonal
  • Clone number
    CIV1.1
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab97658 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 92 kDa.
IP Use at an assay dependent dilution.

Target

  • Function
    Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Belongs to the APC4 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • ANAPC 4 antibody
    • anapc4 antibody
    • Anaphase Promoting Complex Subunit 4 antibody
    • Anaphase-promoting complex subunit 4 antibody
    • APC 4 antibody
    • APC Complex Protein CUT20 antibody
    • APC4 antibody
    • APC4_HUMAN antibody
    • CUT20 antibody
    • Cyclosome subunit 4 antibody
    • LID1 antibody
    see all

References

ab97658 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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