Overview

  • Product nameAnti-Apc5 antibody
    See all Apc5 primary antibodies
  • Description
    Rabbit polyclonal to Apc5
  • Specificityab106487 is predicted not to cross-react with other APC family members.
  • Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 17 amino acid synthetic peptide near the center of Human Apc5 (UniProt Q9UJX4).

  • Positive control
    • Human kidney tissue lysate; Rat kidney tissue

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab106487 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 85 kDa.
IHC-P Use at an assay dependent concentration.

Target

  • FunctionComponent of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesBelongs to the APC5 family.
    Contains 4 TPR repeats.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2510006G12Rik antibody
    • AA408751 antibody
    • AA536819 antibody
    • AA986414 antibody
    • ANAPC 5 antibody
    • ANAPC5 antibody
    • Anaphase promoting complex subunit 5 antibody
    • Anaphase-promoting complex subunit 5 antibody
    • Apc 5 antibody
    • APC5 antibody
    • APC5_HUMAN antibody
    • Cyclosome subunit 5 antibody
    • PDL 108 antibody
    • PDL108 antibody
    • Periodontal ligament fibroblast protein antibody
    • RMC1 antibody
    see all

Anti-Apc5 antibody images

  • Immunofluorescence of Apc5 in rat kidney tissue with ab106487 at 20 ug/mL.

  • Lane 1 : Anti-Apc5 antibody (ab106487) at 1 µg/ml
    Lane 2 : Anti-Apc5 antibody (ab106487) at 2 µg/ml

    Lane 1 : Human kidney tissue lysate
    Lane 2 : Human kidney tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 85 kDa
  • ab106487, at 5 µg/ml, staining Apc5 in Rat kidney tissue by Immunohistochemistry.

References for Anti-Apc5 antibody (ab106487)

ab106487 has not yet been referenced specifically in any publications.

Product Wall

There is 100% homology between the immunogen and bovine sequence.

I hope this is helpful. Please contact me again if you have any further questions.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"