Overview

  • Product nameAnti-Apc5 antibody
    See all Apc5 primary antibodies
  • Description
    Rabbit polyclonal to Apc5
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide conjugated to KLH derived from an internal sequence of Human Apc5.

  • Positive control
    • Human Small Intestine and Human Placenta tissues, Human kidney tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab113359 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 85 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionComponent of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesBelongs to the APC5 family.
    Contains 4 TPR repeats.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2510006G12Rik antibody
    • AA408751 antibody
    • AA536819 antibody
    • AA986414 antibody
    • ANAPC 5 antibody
    • ANAPC5 antibody
    • Anaphase promoting complex subunit 5 antibody
    • Anaphase-promoting complex subunit 5 antibody
    • Apc 5 antibody
    • APC5 antibody
    • APC5_HUMAN antibody
    • Cyclosome subunit 5 antibody
    • PDL 108 antibody
    • PDL108 antibody
    • Periodontal ligament fibroblast protein antibody
    • RMC1 antibody
    see all

Anti-Apc5 antibody images

  • Lane 1 : Anti-Apc5 antibody (ab113359) at 1 µg/ml
    Lane 2 : Anti-Apc5 antibody (ab113359) at 2 µg/ml

    Lane 1 : Human kidney tissue lysate
    Lane 2 : Human kidney tissue lysate


    Predicted band size : 85 kDa
  • Staining of Human Apc5 in a Formalin/PFA-fixed paraffin-embedded section of Human Small Intestine using ab113359 at a concentration of 5 µg/ml.
  • Staining of Human Apc5 in a Formalin/PFA-fixed paraffin-embedded section of Human Placenta using ab113359 at a concentration of 5 µg/ml.

References for Anti-Apc5 antibody (ab113359)

ab113359 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113359.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"