Overview

  • Product nameAnti-Apelin antibody
    See all Apelin primary antibodies
  • Description
    Rabbit polyclonal to Apelin
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide from the C terminal region of Human Apelin.

  • Positive control
    • U87, MCF7, HeLa, MM453 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab125213 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 9 kDa. The detection limit for ab125213 is approximately 1ng/lane under non-reducing and reducing conditions.

Target

  • FunctionEndogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior.
  • Tissue specificityExpressed in the brain with highest levels in the frontal cortex, thalamus, hypothalamus and midbrain. Secreted by the mammary gland into the colostrum and the milk.
  • Sequence similaritiesBelongs to the apelin family.
  • Post-translational
    modifications
    Several active peptides may be produced by proteolytic processing of the peptide precursor.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • AGTRL1 ligand antibody
    • APEL antibody
    • APEL_HUMAN antibody
    • Apelin-13 antibody
    • APJ endogenous ligand antibody
    • Apln antibody
    • XNPEP2 antibody
    see all

Anti-Apelin antibody images

  • All lanes : Anti-Apelin antibody (ab125213) at 1 µg/ml

    Lane 1 : U87 whole cell lysate
    Lane 2 : MCF7 whole cell lysate
    Lane 3 : HeLa whole cell lysate
    Lane 4 : MM453 whole cell lysate


    Predicted band size : 9 kDa

References for Anti-Apelin antibody (ab125213)

ab125213 has not yet been referenced specifically in any publications.

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