Overview

  • Product nameAnti-APIP antibody [19F461]
    See all APIP primary antibodies
  • Description
    Mouse monoclonal [19F461] to APIP
  • SpecificityThis monoclonal antibody can be used for detection of APIP and APIP2.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein.

  • Positive control
    • HeLa or 293 cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: 0.2% Gelatin, PBS
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number19F461
  • IsotypeIgG2b
  • Light chain typekappa
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab22060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 27 kDa.

Target

  • FunctionCatalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Has an anti-apoptotic function and prevents muscle ischemic damage. Inhibits the cytochrome c-dependent and APAF1-mediated cell death.
  • Tissue specificityUbiquitously expressed with high expression in skeletal muscle, heart and kidney.
  • PathwayAmino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.
  • Sequence similaritiesBelongs to the aldolase class II family. MtnB subfamily.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apaf1 Interacting Protein antibody
    • APAF1-interacting protein antibody
    • APIP antibody
    • APIP2 antibody
    • CG129 antibody
    • CGI 29 antibody
    • CGI29 antibody
    • dJ179L10.2 antibody
    • MMRP19 antibody
    • Monocyte/macrophage protein 19 antibody
    • MTNB_HUMAN antibody
    • MTRu 1 P dehydratase antibody
    • MTRu-1-P dehydratase antibody
    • Probable methylthioribulose 1 phosphate dehydratase antibody
    • Probable methylthioribulose-1-phosphate dehydratase antibody
    see all

Anti-APIP antibody [19F461] images

  • Western blot analysis of APIP2 in A) recombinant protein, B) HeLa, and C) 293 whole cell lysate using ab22060 at 2 ug/ml.

References for Anti-APIP antibody [19F461] (ab22060)

ab22060 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"