Anti-APIP antibody (ab154258)
Key features and details
- Rabbit polyclonal to APIP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-APIP antibody -
Description
Rabbit polyclonal to APIP -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Cow -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 1-242 of Human APIP (Uniprot ID: Q96GX9).
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Positive control
- 293T, A431, H1299, HeLa, HepG2, Molt4, Raji whole cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab154258 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 27 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 27 kDa. |
Target
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Function
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Has an anti-apoptotic function and prevents muscle ischemic damage. Inhibits the cytochrome c-dependent and APAF1-mediated cell death. -
Tissue specificity
Ubiquitously expressed with high expression in skeletal muscle, heart and kidney. -
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6. -
Sequence similarities
Belongs to the aldolase class II family. MtnB subfamily. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 508345 Cow
- Entrez Gene: 51074 Human
- Entrez Gene: 56369 Mouse
- Omim: 612491 Human
- SwissProt: Q0VCJ2 Cow
- SwissProt: Q96GX9 Human
- SwissProt: Q8BP46 Mouse
- SwissProt: Q9WVQ5 Mouse
see all -
Alternative names
- Apaf1 Interacting Protein antibody
- APAF1-interacting protein antibody
- APIP antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab154258 has not yet been referenced specifically in any publications.