The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesELISA: antibody detection limit is 1/1000.
WB: Use at a concentration of 0.5 - 1.5 µg/ml. Predicted molecular weight: 23 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionHost cellular restriction factor that may have antiviral activities against exogenous and endogenous viruses, as well as retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Tissue specificityExpressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary.
Sequence similaritiesBelongs to the cytidine and deoxycytidylate deaminase family.