Anti-Apolipoprotein B antibody [1605] (ab20839)

Overview

  • Product nameAnti-Apolipoprotein B antibody [1605]
    See all Apolipoprotein B primary antibodies
  • Description
    Mouse monoclonal [1605] to Apolipoprotein B
  • Specificityab20839 does not cross-react with Apo A-I or Apo A-II.
  • Tested applicationsSuitable for: ELISA, RIAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Serum LDL (purified) (Human).

Properties

Applications

Our Abpromise guarantee covers the use of ab20839 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
RIA Use at an assay dependent dilution.

Target

  • FunctionApolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
  • Involvement in diseaseHypobetalipoproteinemia, familial, 1
    Familial ligand-defective apolipoprotein B-100
    Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
  • Sequence similaritiesContains 1 vitellogenin domain.
  • Post-translational
    modifications
    Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
  • Cellular localizationCytoplasm. Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apo B-100 antibody
    • Apo B-48 antibody
    • ApoB 100 antibody
    • ApoB 48 antibody
    • APOB antibody
    • APOB_HUMAN antibody
    • Apolipoprotein B 100 antibody
    • Apolipoprotein B antibody
    • Apolipoprotein B-48 antibody
    • Apolipoprotein B48 antibody
    • FLDB antibody
    • LDLCQ4 antibody
    see all

References for Anti-Apolipoprotein B antibody [1605] (ab20839)

ab20839 has not yet been referenced specifically in any publications.

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