Anti-Apolipoprotein B antibody [1607] (ab20326)

Overview

  • Product nameAnti-Apolipoprotein B antibody [1607]
    See all Apolipoprotein B primary antibodies
  • Description
    Mouse monoclonal [1607] to Apolipoprotein B
  • SpecificityNo cross reactivity with Apolipoprotein A I or Apolipoprotein A II has been demonstrated.
  • Tested applicationsSuitable for: RIA, Competitive ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified Human serum LDL.

Applications

Our Abpromise guarantee covers the use of ab20326 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
RIA
Competitive ELISA
  • Application notescELISA: Use at an assay dependent dilution.
    cRIA: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionApolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
    • Involvement in diseaseHypobetalipoproteinemia, familial, 1
      Familial ligand-defective apolipoprotein B-100
      Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
    • Sequence similaritiesContains 1 vitellogenin domain.
    • Post-translational
      modifications
      Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
    • Cellular localizationCytoplasm. Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • Apo B-100 antibody
      • Apo B-48 antibody
      • ApoB 100 antibody
      • ApoB 48 antibody
      • APOB antibody
      • APOB_HUMAN antibody
      • Apolipoprotein B 100 antibody
      • Apolipoprotein B antibody
      • Apolipoprotein B-48 antibody
      • Apolipoprotein B48 antibody
      • FLDB antibody
      • LDLCQ4 antibody
      see all

    References for Anti-Apolipoprotein B antibody [1607] (ab20326)

    ab20326 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. Unfortunately I do not have a specific protocol for competitive EIA or RIA using this antiserum. RIA stands for radioimmunoassay and EIA is an acronym for enzymeimmunoassay. If you are interested in the basics of...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"