Overview

  • Product name
    Anti-Apolipoprotein B antibody (Biotin)
    See all Apolipoprotein B primary antibodies
  • Description
    Goat polyclonal to Apolipoprotein B (Biotin)
  • Conjugation
    Biotin
  • Specificity
    Ab20898 binds to Apolipoprotein B. No cross reaction with human plasma Apo AI, Apo AII, Apo CI, Apo CII, Apo CIII and Apo E.
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human LDL.

Properties

Applications

Our Abpromise guarantee covers the use of ab20898 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/4000 - 1/40000. Predicted molecular weight: 516 kDa.

Dilution optimised using Chromogenic detection. Can be used for detection of Apo B-100 in plasma and lipoproteins.

ELISA 1/4000 - 1/40000.

Target

  • Function
    Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
  • Involvement in disease
    Hypobetalipoproteinemia, familial, 1
    Familial ligand-defective apolipoprotein B-100
    Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
  • Sequence similarities
    Contains 1 vitellogenin domain.
  • Post-translational
    modifications
    Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
  • Cellular localization
    Cytoplasm. Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apo B-100 antibody
    • Apo B-48 antibody
    • ApoB 100 antibody
    • ApoB 48 antibody
    • APOB antibody
    • APOB_HUMAN antibody
    • Apolipoprotein B (including Ag(x) antigen) antibody
    • Apolipoprotein B 100 antibody
    • Apolipoprotein B antibody
    • Apolipoprotein B-48 antibody
    • Apolipoprotein B48 antibody
    • FLDB antibody
    • LDLCQ4 antibody
    see all

References

This product has been referenced in:
  • Dernick G  et al. Multidimensional profiling of plasma lipoproteins by size exclusion chromatography followed by reverse-phase protein arrays. J Lipid Res 52:2323-31 (2011). Read more (PubMed: 21971713) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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