Overview

  • Product nameAnti-Apolipoprotein B antibody (HRP)
    See all Apolipoprotein B primary antibodies
  • Description
    Goat polyclonal to Apolipoprotein B (HRP)
  • ConjugationHRP
  • SpecificityAb20047 binds to Human Apo B-48/100. No cross- reaction with human Apo AI, Apo AII, Apo CI, Apo CII, Apo CIII and Apo E.
  • Tested applicationsSuitable for: Dot blot, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified): Human LDL

Applications

Our Abpromise guarantee covers the use of ab20047 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Dot blot 1/2500 - 1/10000.
ELISA 1/2500 - 1/10000.

Target

  • FunctionApolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
  • Involvement in diseaseHypobetalipoproteinemia, familial, 1
    Familial ligand-defective apolipoprotein B-100
    Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
  • Sequence similaritiesContains 1 vitellogenin domain.
  • Post-translational
    modifications
    Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
  • Cellular localizationCytoplasm. Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apo B-100 antibody
    • Apo B-48 antibody
    • ApoB 100 antibody
    • ApoB 48 antibody
    • APOB antibody
    • APOB_HUMAN antibody
    • Apolipoprotein B 100 antibody
    • Apolipoprotein B antibody
    • Apolipoprotein B-48 antibody
    • Apolipoprotein B48 antibody
    • FLDB antibody
    • LDLCQ4 antibody
    see all

References for Anti-Apolipoprotein B antibody (HRP) (ab20047)

This product has been referenced in:
  • Younis NN  et al. High-density lipoprotein impedes glycation of low-density lipoprotein. Diab Vasc Dis Res : (2012). ELISA ; Human . Read more (PubMed: 22890407) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"