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Goat polyclonal to Apolipoprotein CIII
Human Apo CIII recombinant protein corresponds to N-terminal 99 amino acids
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Preservative: 0.02% Sodium azide
Constituents: 99% PBS, 0.44% Sodium chloride
Concentration information loading...
Protein G purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/2500 - 1/20000. Predicted molecular weight: 11 kDa.
||Use a concentration of 5 µg/ml.
Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.
Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.
Involvement in disease
Defects in APOC3 may be a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
Belongs to the apolipoprotein C3 family.
O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.
Information by UniProt
- APOC3 antibody
- APO C3 antibody
- Apo CIII antibody
has not yet been referenced specifically in any publications.
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