Anti-Apolipoprotein CIII antibody (FITC) (ab27612)

Overview

  • Product nameAnti-Apolipoprotein CIII antibody (FITC)
    See all Apolipoprotein CIII primary antibodies
  • Description
    Goat polyclonal to Apolipoprotein CIII (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Specificitythsi antibody specifically binds to human Apolipoprotein CIII.
  • Tested applicationsSuitable for: ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native APO CII protein (purified) (Human)

  • General notes

    Molar FITC/ Protein ratio is 5.3.

Properties

Applications

Our Abpromise guarantee covers the use of ab27612 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent dilution.

Target

  • FunctionInhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.
  • Tissue specificityConstitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.
  • Involvement in diseaseDefects in APOC3 may be a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
  • Sequence similaritiesBelongs to the apolipoprotein C3 family.
  • Post-translational
    modifications
    O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • APOC3 antibody
    • APO C3 antibody
    • Apo CIII antibody
    • Apo-CIII antibody
    • APOC 3 antibody
    • ApoC III antibody
    • ApoC-III antibody
    • APOC3 antibody
    • APOC3_HUMAN antibody
    • ApoCIII antibody
    • Apolipoprotein C III antibody
    • Apolipoprotein C-III antibody
    • Apolipoprotein C3 antibody
    • ApolipoproteinCIII antibody
    • MGC150353 antibody
    see all

References for Anti-Apolipoprotein CIII antibody (FITC) (ab27612)

ab27612 has not yet been referenced specifically in any publications.

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