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Goat polyclonal to Apolipoprotein CIII (FITC)
FITC. Ex: 493nm, Em: 528nm
thsi antibody specifically binds to human Apolipoprotein CIII.
Full length native APO CII protein (purified) (Human)
Molar FITC/ Protein ratio is 5.3.
Shipped at 4°C. Store at +4°C.
Preservative: 0.02% Sodium Azide
Constituents: 5mg/ml BSA, 75mM Sodium chloride, 75mM PBS, 0.5mM EDTA. pH 7.4
Concentration information loading...
Immunogen affinity purified
Purified by human Apolipoprotein CIII-Sepharose™ affinity column.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use at an assay dependent dilution.
Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.
Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.
Involvement in disease
Defects in APOC3 may be a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
Belongs to the apolipoprotein C3 family.
O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan.
Information by UniProt
- APOC3 antibody
- APO C3 antibody
- Apo CIII antibody
References for Anti-Apolipoprotein CIII antibody (FITC) (ab27612)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"