Anti-Apolipoprotein D antibody (ab113634)

Overview

  • Product nameAnti-Apolipoprotein D antibody
    See all Apolipoprotein D primary antibodies
  • Description
    Sheep polyclonal to Apolipoprotein D
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein produced in E. coli: FHLGKCPNPP VQENFDVNKY PGRWYEIEKI PTTFENGRCI QANYSLMENG KIKVLNQELR ADGTVNQIEG EATPVNLTEP AKLEVKFSWF MPSAPYHILA TDYENYALVY SCTSISQSFH VDFAWILARN VALPPETVDS LKNILTSNNI DVKKMTVTDQ VNCPKLSAHH HHHH, corresponding to amino acids 23-189 of Human Apolipoprotein D. Contains a C terminal His-tag of 7 extra AA. The amino acid sequence corresponds to the UniProt P05090. The following modifications were made: Four amino acid exchanges were introduced at the surface of ApoD (Trp99His, Cys116Ser, Ile118Ser, Leu120Ser) to enhance the solubility of the recombinant protein and another three (Leu23Pro, Pro133Val, Asn134Ala) to facilitate its genetic manipulation.

  • General notesReconstituted antibody can be stored at 4°C for a limited period of time; it does not show decline in activity after one week at 4°C.

Properties

Applications

Our Abpromise guarantee covers the use of ab113634 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 21 kDa.
ELISA Use at an assay dependent dilution.

Target

  • FunctionAPOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.
  • Tissue specificityExpressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.
  • Sequence similaritiesBelongs to the calycin superfamily. Lipocalin family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • APO D antibody
    • Apo-D antibody
    • ApoD antibody
    • APOD protein antibody
    • APOD_HUMAN antibody
    • Apolipoprotein D antibody
    • ApolipoproteinD antibody
    see all

References for Anti-Apolipoprotein D antibody (ab113634)

ab113634 has not yet been referenced specifically in any publications.

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I have done a blast search for you using the immunogen sequnce but it seems that there is only 75% homology between the human and the mouse Apolipoprotein D sequence. This means that the it is un...

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