Anti-Apoptosis enhancing nuclease antibody (ab97915)

Overview

  • Product name
    Anti-Apoptosis enhancing nuclease antibody
  • Description
    Rabbit polyclonal to Apoptosis enhancing nuclease
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 236-297 of Apoptosis enhancing nuclease (NP_073604).

  • Positive control
    • HeLa, HepG2 or MOLT4 cell lines.

Properties

Applications

Our Abpromise guarantee covers the use of ab97915 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 36 kDa.
IHC-P 1/100 - 1/250.

Target

  • Function
    Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.
  • Sequence similarities
    Contains 1 exonuclease domain.
  • Cellular localization
    Nucleus. Nucleus > nucleolus. Localized predomintly in the nucleolus. Translocates from the nucleolus to the nucleoplasm upon apoptosis induction.
  • Information by UniProt
  • Database links
  • Alternative names
    • Aen antibody
    • AEN_HUMAN antibody
    • apoptosis enhancing nuclease antibody
    • Apoptosis-enhancing nuclease antibody
    • Interferon stimulated exonuclease gene 20kDa like 1 antibody
    • Interferon stimulated exonuclease gene 20kDa like 1, isoform CRA_a antibody
    • Interferon-stimulated 20 kDa exonuclease-like 1 antibody
    • ISG20L1 antibody
    • pp12744 antibody
    see all

Images

  • Anti-Apoptosis enhancing nuclease antibody (ab97915) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size : 36 kDa
  • ab97915, at 1/100 dilution, staining Apoptosis enhancing nuclease in Cal27 xenograft tissue by Immunohistochemistry. Formalin-fixed, paraffin-embedded section.

References

ab97915 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab97915.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up