Overview

  • Product name
  • Description
    Rabbit polyclonal to APRIL
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to amino acids 196-210 of Human APRIL.

  • Positive control
    • HL60 and Jurkat cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab3681 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
WB
  • Application notes
    IHC-P: Use at a concentration of 10 µg/ml.
    WB: Use at a concentration of 2 - 4 µg/ml. Predicted molecular weight: 27 kDa. Can be blocked with APRIL peptide (human)

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
    • Tissue specificity
      Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
    • Sequence similarities
      Belongs to the tumor necrosis factor family.
    • Post-translational
      modifications
      The precursor is cleaved by furin.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • A proliferation inducing ligand antibody
      • A proliferation-inducing ligand antibody
      • APRIL antibody
      • CD256 antibody
      • TALL-2 antibody
      • TALL2 antibody
      • TNF related death ligand antibody
      • TNF- and APOL-related leukocyte expressed ligand 2 antibody
      • TNF-related death ligand 1 antibody
      • TNF13_HUMAN antibody
      • TNFSF13 antibody
      • TRDL-1 antibody
      • TRDL1 antibody
      • Tumor necrosis factor (ligand) superfamily, member 13 antibody
      • Tumor necrosis factor ligand superfamily member 13 antibody
      • Tumor necrosis factor like protein ZTNF2 antibody
      • Tumor necrosis factor related death ligand 1 antibody
      • UNQ383/PRO715 antibody
      • ZTNF2 antibody
      see all

    Images

    • Lane 1 : Anti-APRIL antibody (ab3681) at 1 µg/ml
      Lane 2 : Anti-APRIL antibody (ab3681) at 2 µg/ml
      Lane 3 : Anti-APRIL antibody (ab3681) at 4 µg/ml

      Lane 1 : Jurkat cells
      Lane 2 : Jurkat cells
      Lane 3 : Jurkat cells


      Predicted band size : 27 kDa
      Observed band size : 27 kDa
    • Immunohistochemistry of APRIL in human prostate tissue with APRIL antibody at 10 µg/ml.

    References

    ab3681 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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