Overview

  • Product nameAnti-Aprotinin antibody [35]
  • Description
    Mouse monoclonal [35] to Aprotinin
  • Tested applicationsSuitable for: WB, Indirect ELISAmore details
  • Species reactivity
    Reacts with: Cow
  • Immunogen

    Aprotinin from bovine lung adsorbed onto aluminum hydroxide gel

  • Positive control
    • Bovine lung

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 15mM Sodium Azide
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number35
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab82110 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 11 kDa.
Indirect ELISA 1/33000.

Target

  • RelevanceAprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. It is present in blood and in most tissues, with a high concentration in lung, inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, Aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins. Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids arranged in a single polypeptide chain, cross-linked by three disulfide bridges.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • Basic protease inhibitor antibody
    • BPI antibody
    • BPTI antibody
    • Pancreatic trypsin inhibitor antibody
    • PTI antibody
    see all

References for Anti-Aprotinin antibody [35] (ab82110)

This product has been referenced in:
  • Zlokovic BV  et al. Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer's amyloid ß-peptide elimination from the brain. J Neurochem 115:1077-89 (2010). WB, ELISA . Read more (PubMed: 20854368) »

See 1 Publication for this product

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The two anti-aprotinin antibodies we have in our catalogue (ab82110 and ab121046) have both been raised against full length aprotinin from cow (SwissProt reference http://www.unip...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"