Anti-Aquaporin 0 antibody (ab15077)

Overview

  • Product nameAnti-Aquaporin 0 antibody
    See all Aquaporin 0 primary antibodies
  • Description
    Rabbit polyclonal to Aquaporin 0
  • Specificityab15077 recognises aquaporin 0.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Cow
  • Immunogen

    A 17 AA synthetic peptide within the carboxy terminal domain of human Aquaporin 0.

Properties

Applications

Our Abpromise guarantee covers the use of ab15077 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notesELISA: Use at a concentration of 0.5 - 1 µg/ml.
    WB: Use at a concentration of 1 - 10 µg/ml with ECL detection. Predicted molecular weight: 28 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionWater channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.
    • Tissue specificityMajor component of lens fiber gap junctions.
    • Involvement in diseaseCataract 15, multiple types
    • Sequence similaritiesBelongs to the MIP/aquaporin (TC 1.A.8) family.
    • DomainAquaporins contain two tandem repeats each containing two membrane-spanning helices and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). Each tandem repeat contains a loop and a short helix that enter and leave the lipid bilayer on the same side.
    • Post-translational
      modifications
      Subject to partial proteolytic cleavage in the eye lens core. Partial proteolysis promotes interactions between tetramers from adjoining membranes.
    • Cellular localizationCell membrane. Cell junction > gap junction.
    • Information by UniProt
    • Database links
    • Alternative names
      • AQP 0 antibody
      • AQP0 antibody
      • Aquaporin antibody
      • Aquaporin-0 antibody
      • Aquaporin0 antibody
      • Lens fiber major intrinsic protein antibody
      • LIM 1 antibody
      • LIM1 antibody
      • Major intrinsic protein 26kD antibody
      • Major intrinsic protein of lens fiber antibody
      • MIP 26 antibody
      • mip antibody
      • MIP_HUMAN antibody
      • MIP26 antibody
      • MP 26 antibody
      • MP26 antibody
      • PALM antibody
      see all

    References for Anti-Aquaporin 0 antibody (ab15077)

    ab15077 has not yet been referenced specifically in any publications.

    Product Wall

    いつもお世話になっております。 この度はお問合せいただきましてありがとうございます。 申し訳ありませんが、ab15077のpositive controlを取り扱いしておりません。しかしながら、bovine lens fiberはpositive controlとしてご使用できます。 もしよければ、この抗体や、似ているクローンの文献情報は以下に添付いたします。 Molecular Vision 2003; 9:497-501 [http://www.molvis.org/mo...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"