The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/2000. Predicted molecular weight: 29 kDa.
1/100. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
FunctionForms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Tissue specificityExpressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.
Sequence similaritiesBelongs to the MIP/aquaporin (TC 1.A.8) family.
DomainAquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
HEK293T cells transfected with either RC205304 overexpressing plasmid (Red) or empty vector control plasmid (Blue) were immunostained by ab117970 at a dilution of 1/100, and then analyzed by flow cytometry.
References for Anti-Aquaporin 1 antibody [10C11] (ab117970)
has not yet been referenced specifically in any publications.
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