Anti-Aquaporin 9/AQP-9 antibody (ab15127)
Key features and details
- Rabbit polyclonal to Aquaporin 9/AQP-9
- Suitable for: ELISA, WB
- Reacts with: Rat
- Isotype: IgG
Overview
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Product name
Anti-Aquaporin 9/AQP-9 antibody
See all Aquaporin 9/AQP-9 primary antibodies -
Description
Rabbit polyclonal to Aquaporin 9/AQP-9 -
Host species
Rabbit -
Tested applications
Suitable for: ELISA, WBmore details -
Species reactivity
Reacts with: Rat -
Immunogen
Synthetic peptide corresponding to Rat Aquaporin 9/AQP-9 (C terminal).
Database link: P56627 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Constituent: 40% Glycerol -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab15127 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA | ||
WB |
Notes |
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WB: 1/1000 - 1/5000, or 1-10 ug/ml for affinity purified antibody using ECL. Predicted molecular weight: 35.4 kDa.
Immunohistochemistry & Immunofluorescence: Neat serum can be used at 1:500 or more.
Control peptides, because of their low MW (<3kD), are not suitable for Western. It should be used for ELISA or antibody blocking to confirm antibody specificity
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Function
Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol. -
Tissue specificity
Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen. -
Sequence similarities
Belongs to the MIP/aquaporin (TC 1.A.8) family. -
Domain
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 65054 Rat
- SwissProt: P56627 Rat
- Unigene: 30018 Rat
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Alternative names
- AQP 9 antibody
- AQP-9 antibody
- Aqp9 antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab15127 has been referenced in 4 publications.
- Wang X et al. MEX3A knockdown inhibits the development of pancreatic ductal adenocarcinoma. Cancer Cell Int 20:63 (2020). PubMed: 32140076
- Chang L et al. Long Non-coding RNA LINC00320 Inhibits Tumorigenicity of Glioma Cells and Angiogenesis Through Downregulation of NFKB1-Mediated AQP9. Front Cell Neurosci 14:542552 (2020). PubMed: 33414706
- Han X et al. Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsia-Like Seizure. Int J Mol Sci 19:N/A (2018). PubMed: 29351212
- Sun Z et al. Recombinant hirudin treatment modulates aquaporin-4 and aquaporin-9 expression after intracerebral hemorrhage in vivo. Mol Biol Rep 36:1119-27 (2009). WB, IF, IHC ; Rat . PubMed: 18574711