Overview

  • Product nameArachidonic acid
  • Description
    ω-6 Polyunsaturated fatty acid, precursor of eicosanoids
  • Biological descriptionMajor precursor in the production of eicosanoids and important cellular signaling mediator. Endogenous free fatty acid released from phospholipids by PLA2. Metabolised by COX, lipoxygenase and cytochrome p450s to form a variety of eicosanoids including PGs and LTs.
  • Purity> 98%

Properties

    References for Arachidonic acid (ab120916)

    This product has been referenced in:
    • Astudillo AM  et al. Dynamics of arachidonic acid mobilization by inflammatory cells. Biochim Biophys Acta 1821:249-56 (2012). Read more (PubMed: 22155285) »
    • Higuchi Y  et al. Arachidonic acid promotes glutamate-induced cell death associated with necrosis by 12- lipoxygenase activation in glioma cells. Life Sci 80:1856-64 (2007). Read more (PubMed: 17400255) »
    • Nakanishi M & Rosenberg DW Roles of cPLA2alpha and arachidonic acid in cancer. Biochim Biophys Acta 1761:1335-43 (2006). Read more (PubMed: 17052951) »

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