Anti-Archaemetzincin 2 antibody - Catalytic domain (ab65885)

Overview

  • Product nameAnti-Archaemetzincin 2 antibody - Catalytic domain
    See all Archaemetzincin 2 primary antibodies
  • Description
    Rabbit polyclonal to Archaemetzincin 2 - Catalytic domain
  • Specificityab65885 recognizes all of the forms of Archaemetzincin 2. We have a range of domain specific antibodies for this target. For a full list please see all Archaemetzincin 2 antibodies.
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide based on the catalytic domain of human Archaemetzincin 2.

  • Positive control
    • HFL-1 lysate treated with TPA, IL1 beta, beta-estradiol or Testosterone, or serum free.

Properties

  • FormLiquid
  • Storage instructionsStore at -20°C. Stable for 12 months at -20°C
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: 50% Glycerol, PBS, 500mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab65885 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/1000 when using colorimetric substrates such as BCIP/NBT, and 1/5000 for chemiluminescent substrates. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionZinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze either neurogranin or angiotensin-2.
    • Tissue specificityPredominantly expressed in heart and testis. Also expressed at lower levels in kidney, liver, pancreas, lung, brain and placenta. Expressed in fetal tissues such as kidney, liver, lung and brain.
    • Sequence similaritiesBelongs to the peptidase M54 family.
    • Information by UniProt
    • Database links
    • Alternative names
      • AMZ2 antibody
      • AMZ2_HUMAN antibody
      • Archaelysin family metallopeptidase 2 antibody
      • Archaemetzincin 2 antibody
      • Archaemetzincin-2 antibody
      • Archeobacterial metalloproteinase like protein 2 antibody
      • Archeobacterial metalloproteinase-like protein 2 antibody
      see all

    Anti-Archaemetzincin 2 antibody - Catalytic domain images

    • All lanes : Anti-Archaemetzincin 2 antibody - Catalytic domain (ab65885) at 1/5000 dilution

      Lane 1 : HFL-1 lysate (1/4 dilution) - Serum Free
      Lane 2 : HFL-1 lysate (1/4 dilution) treated with TPA
      Lane 3 : HFL-1 lysate (1/4 dilution) treated with IL1 beta
      Lane 4 : HFL-1 lysate (1/4 dilution) treated with beta-estradiol
      Lane 5 : HFL-1 lysate (1/4 dilution) treated with testosterone

      Lysates/proteins at 35 µl per lane.


      Predicted band size : 41 kDa
      Observed band size : 41 kDa
      Additional bands at : 110 kDa,45 kDa,49 kDa (possible isoform),66 kDa. We are unsure as to the identity of these extra bands.

    References for Anti-Archaemetzincin 2 antibody - Catalytic domain (ab65885)

    ab65885 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"