Overview

  • Product name
    Anti-Arf6 antibody - C-terminal
  • Description
    Rabbit polyclonal to Arf6 - C-terminal
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human Arf6 (C terminal). Peptide corresponds to 19 amino acids.
    Database link: NP_001654

  • Positive control
    • Rat liver tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab181000 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 20 kDa.

Target

  • Function
    GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May modulate vesicle budding and uncoating within the Golgi apparatus. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in the regulation of dendritic spine development (By similarity). Contributes to the regulation of dendritic branching and filopodia extension.
  • Tissue specificity
    Ubiquitous, with higher levels in heart, substantia nigra, and kidney.
  • Sequence similarities
    Belongs to the small GTPase superfamily. Arf family.
  • Cellular localization
    Golgi apparatus. Cell membrane. Endosome membrane. Cell membrane. Cell projection > filopodium membrane. Recruited to the cell membrane in association with CYTH2 and ARL4C.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADP-ribosylation factor 6 antibody
    • ARF6 antibody
    • ARF6_HUMAN antibody

Images

References

ab181000 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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