Overview

  • Product nameAnti-ARFGAP3 antibody
    See all ARFGAP3 primary antibodies
  • Description
    Goat polyclonal to ARFGAP3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Dog, Human
  • Immunogen

    Synthetic peptide:

    C-NGVVTSIQDRYGS

    , corresponding to C terminal amino acids 504-516 of Human ARFGAP3 (Peptide available as ab22801.)

  • General notesPrincipal Names: ARFGAP1, ADP ribosylation factor GTPase activating protein 1, ARFGAP3. GenBank Accession Number: NP055385 LocusLink ID: 26286


    ARFs are critical in vesicular trafficking pathway.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab1308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Can be blocked with Human ARFGAP3 peptide (ab22801).

Approx 55-60kDa band seen in Mouse Brain extracts.

Target

  • FunctionGTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
  • Tissue specificityWidely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.
  • Sequence similaritiesContains 1 Arf-GAP domain.
  • Developmental stageExpressed at higher level in adult thymus, brain and lung, than in corresponding fetal tissues. Expressed at lower level in spleen, heart, kidney and liver during development.
  • Cellular localizationCytoplasm. Golgi apparatus membrane. Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADP ribosylation factor GTPase activating protein 1 antibody
    • ADP ribosylation factor GTPase activating protein 3 antibody
    • ADP-ribosylation factor GTPase-activating protein 3 antibody
    • ARF GAP 3 antibody
    • ARFG3_HUMAN antibody
    • ArfGAP 3 antibody
    • ARFGAP1 antibody
    • ARFGAP3 antibody
    • FLJ45618 antibody
    see all

Anti-ARFGAP3 antibody images

  • ARFGAP3 staining (2µg/ml) of Mouse Brain extracts (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence

References for Anti-ARFGAP3 antibody (ab1308)

ab1308 has not yet been referenced specifically in any publications.

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