Anti-Argonaute-2 antibody [2E12-1C9] - ChIP Grade (ab57113)

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ab57113 has been referenced in 70 publications.

  • Özata DM  et al. Loss of miR-514a-3p regulation of PEG3 activates the NF-kappa B pathway in human testicular germ cell tumors. Cell Death Dis 8:e2759 (2017). WB, IP ; Human . PubMed: 28471449
  • Beltrami C  et al. Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis. Mol Ther 25:679-693 (2017). PubMed: 28159509
  • Du Z  et al. Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer. Nat Commun 7:10982 (2016). PubMed: 26975529
  • Sharma NR  et al. Cell Type- and Tissue Context-dependent Nuclear Distribution of Human Ago2. J Biol Chem 291:2302-9 (2016). PubMed: 26699195
  • Iavello A  et al. Role of Alix in miRNA packaging during extracellular vesicle biogenesis. Int J Mol Med 37:958-66 (2016). WB . PubMed: 26935291
  • Hua WF  et al. RBM24 suppresses cancer progression by upregulating miR-25 to target MALAT1 in nasopharyngeal carcinoma. Cell Death Dis 7:e2352 (2016). PubMed: 27584791
  • Atwood BL  et al. Human Argonaute 2 Is Tethered to Ribosomal RNA through MicroRNA Interactions. J Biol Chem 291:17919-28 (2016). PubMed: 27288410
  • Wu HL  et al. Demystifying the mechanistic and functional aspects of p21 gene activation with double-stranded RNAs in human cancer cells. J Exp Clin Cancer Res 35:145 (2016). PubMed: 27639690
  • Kalantari R  et al. Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells. RNA 22:1085-98 (2016). WB ; Human . PubMed: 27198507
  • Rajgor D  et al. Identification of novel nesprin-1 binding partners and cytoplasmic matrin-3 in processing bodies. Mol Biol Cell 27:3894-3902 (2016). WB ; Human . PubMed: 27733621
  • Polioudakis D  et al. MiR-191 Regulates Primary Human Fibroblast Proliferation and Directly Targets Multiple Oncogenes. PLoS One 10:e0126535 (2015). WB . PubMed: 25992613
  • Marin-Vicente C  et al. RRP6/EXOSC10 is required for the repair of DNA double-strand breaks by homologous recombination. J Cell Sci 128:1097-107 (2015). PubMed: 25632158
  • Kang D  et al. EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell Survival. PLoS Pathog 11:e1004979 (2015). PubMed: 26070070
  • Wang T  et al. MiR-30a upregulates BCL2A1, IER3 and cyclin D2 expression by targeting FOXL2. Oncol Lett 9:967-971 (2015). WB . PubMed: 25621074
  • Li P  et al. Argonaute 2 and nasopharyngeal carcinoma: a genetic association study and functional analysis. BMC Cancer 15:862 (2015). WB, IHC . PubMed: 26545861
  • Liu J  et al. Modulation of Splicing by Single-Stranded Silencing RNAs. Nucleic Acid Ther 25:113-20 (2015). PubMed: 25757055
  • Xie H  et al. Novel functions and targets of miR-944 in human cervical cancer cells. Int J Cancer 136:E230-41 (2015). IP . PubMed: 25156441
  • Polioudakis D  et al. miR-503 represses human cell proliferation and directly targets the oncogene DDHD2 by non-canonical target pairing. BMC Genomics 16:40 (2015). IP . PubMed: 25653011
  • Guo X  et al. MicroRNA-16 modulates HuR regulation of cyclin E1 in breast cancer cells. Int J Mol Sci 16:7112-32 (2015). PubMed: 25830480
  • Woolnough JL  et al. Argonaute 2 Binds Directly to tRNA Genes and Promotes Gene Repression in cis. Mol Cell Biol 35:2278-94 (2015). PubMed: 25918241
  • Yi T  et al. eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference. Nat Commun 6:7194 (2015). WB, IP . PubMed: 26018492
  • Ma Y  et al. Functional screen reveals essential roles of miR-27a/24 in differentiation of embryonic stem cells. EMBO J 34:361-78 (2015). PubMed: 25519956
  • Zhang Y  et al. MicroRNAs in the axon locally mediate the effects of chondroitin sulfate proteoglycans and cGMP on axonal growth. Dev Neurobiol 75:1402-19 (2015). PubMed: 25788427
  • Gagnon KT  et al. RNAi factors are present and active in human cell nuclei. Cell Rep 6:211-21 (2014). PubMed: 24388755
  • Martin HC  et al. Imperfect centered miRNA binding sites are common and can mediate repression of target mRNAs. Genome Biol 15:R51 (2014). PubMed: 24629056
  • Gagnon KT  et al. Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading. Nat Protoc 9:2045-60 (2014). PubMed: 25079428
  • Furuse Y  et al. Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells. PLoS One 9:e106434 (2014). IP . PubMed: 25184567
  • Booy EP  et al. The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1. Nucleic Acids Res 42:3346-61 (2014). Human . PubMed: 24369427
  • Flores O  et al. Differential RISC association of endogenous human microRNAs predicts their inhibitory potential. Nucleic Acids Res 42:4629-39 (2014). IP ; Human . PubMed: 24464996
  • Parnas O  et al. Analysis of the mRNA targetome of microRNAs expressed by Marek's disease virus. MBio 5:e01060-13 (2014). IP . PubMed: 24449754
  • Skalsky RL  et al. Evolutionary conservation of primate lymphocryptovirus microRNA targets. J Virol 88:1617-35 (2014). IP . PubMed: 24257599
  • Wei Y  et al. Importin 8 regulates the transport of mature microRNAs into the cell nucleus. J Biol Chem 289:10270-5 (2014). IP ; Mouse . PubMed: 24596094
  • Rajgor D  et al. Mammalian microtubule P-body dynamics are mediated by nesprin-1. J Cell Biol 205:457-475 (2014). PubMed: 24862572
  • Bogerd HP  et al. Derivation and characterization of Dicer- and microRNA-deficient human cells. RNA 20:923-37 (2014). PubMed: 24757167
  • Ferreira R  et al. Argonaute-2 promotes miR-18a entry in human brain endothelial cells. J Am Heart Assoc 3:e000968 (2014). PubMed: 24837588
  • Lv Z  et al. Argonaute 2 in cell-secreted microvesicles guides the function of secreted miRNAs in recipient cells. PLoS One 9:e103599 (2014). IP ; Human . PubMed: 25072345
  • Whisnant AW  et al. In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms. MBio 4:e000193 (2013). CHIPseq . PubMed: 23592263
  • Polioudakis D  et al. A Myc-microRNA network promotes exit from quiescence by suppressing the interferon response and cell-cycle arrest genes. Nucleic Acids Res 41:2239-54 (2013). IP ; Human . PubMed: 23303785
  • Hansen TB  et al. Natural RNA circles function as efficient microRNA sponges. Nature 495:384-8 (2013). WB . PubMed: 23446346
  • Roberts JC  et al. Expression of microRNA-184 in keratinocytes represses argonaute 2. J Cell Physiol N/A:N/A (2013). PubMed: 23696368
  • Flores O  et al. Mutational inactivation of herpes simplex virus 1 microRNAs identifies viral mRNA targets and reveals phenotypic effects in culture. J Virol 87:6589-603 (2013). PubMed: 23536669
  • Liang XH & Crooke ST RNA helicase A is not required for RISC activity. Biochim Biophys Acta 1829:1092-101 (2013). PubMed: 23895878
  • Matsui M  et al. Promoter RNA links transcriptional regulation of inflammatory pathway genes. Nucleic Acids Res N/A:N/A (2013). WB . PubMed: 23999091
  • Ozgur S & Stoecklin G Role of Rck-Pat1b binding in assembly of processing-bodies. RNA Biol 10:528-39 (2013). Human . PubMed: 23535175
  • Mishra R & Singh SK HIV-1 Tat C modulates expression of miRNA-101 to suppress VE-cadherin in human brain microvascular endothelial cells. J Neurosci 33:5992-6000 (2013). WB ; Human . PubMed: 23554480
  • Caramuta S  et al. Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma. Endocr Relat Cancer 20:551-64 (2013). IP . PubMed: 23671264
  • Pare JM  et al. Hsp90 cochaperones p23 and FKBP4 physically interact with hAgo2 and activate RNA interference-mediated silencing in mammalian cells. Mol Biol Cell 24:2303-10 (2013). PubMed: 23741051
  • Wei W  et al. A role for small RNAs in DNA double-strand break repair. Cell 149:101-12 (2012). PubMed: 22445173
  • Hu J  et al. Promoter-associated small double-stranded RNA interacts with heterogeneous nuclear ribonucleoprotein A2/B1 to induce transcriptional activation. Biochem J 447:407-16 (2012). PubMed: 23035981
  • Li L  et al. Argonaute 2 complexes selectively protect the circulating microRNAs in cell-secreted microvesicles. PLoS One 7:e46957 (2012). PubMed: 23077538
  • Hu J  et al. Mechanism of allele-selective inhibition of huntingtin expression by duplex RNAs that target CAG repeats: function through the RNAi pathway. Nucleic Acids Res 40:11270-80 (2012). ChIP . PubMed: 23042244
  • Agra Andrieu N  et al. Cyclooxygenase-2 is a target of microRNA-16 in human hepatoma cells. PLoS One 7:e50935 (2012). WB . PubMed: 23226427
  • Lu C  et al. Moloney leukemia virus type 10 inhibits reverse transcription and retrotransposition of intracisternal a particles. J Virol 86:10517-23 (2012). PubMed: 22811528
  • Zhang L  et al. Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA. Cell Res 22:107-26 (2012). PubMed: 21931358
  • Xie H  et al. miR-205 expression promotes cell proliferation and migration of human cervical cancer cells. PLoS One 7:e46990 (2012). IP . PubMed: 23056551
  • Van Duyne R  et al. Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery. PLoS One 7:e40662 (2012). PubMed: 22808228
  • Kim SW  et al. MicroRNAs miR-125a and miR-125b constitutively activate the NF-?B pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20). Proc Natl Acad Sci U S A 109:7865-70 (2012). PubMed: 22550173
  • Ho JJ  et al. Functional importance of dicer protein in the adaptive cellular response to hypoxia. J Biol Chem 287:29003-20 (2012). WB ; Human . PubMed: 22745131
  • Behrman S  et al. A CHOP-regulated microRNA controls rhodopsin expression. J Cell Biol 192:919-27 (2011). WB ; Human . PubMed: 21402790
  • Joyce CE  et al. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. Hum Mol Genet 20:4025-40 (2011). WB . PubMed: 21807764
  • Challagundla KB  et al. Ribosomal protein L11 recruits miR-24/miRISC to repress c-Myc expression in response to ribosomal stress. Mol Cell Biol 31:4007-21 (2011). PubMed: 21807902
  • Liang XH & Crooke ST Depletion of key protein components of the RISC pathway impairs pre-ribosomal RNA processing. Nucleic Acids Res : (2011). IF . PubMed: 21321021
  • Arroyo JD  et al. Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci U S A 108:5003-8 (2011). PubMed: 21383194
  • Giles KE  et al. Maintenance of a constitutive heterochromatin domain in vertebrates by a Dicer-dependent mechanism. Nat Cell Biol 12:94-9; sup pp 1-6 (2010). ChIP ; Chicken . PubMed: 20010811
  • Wang X  et al. Moloney leukemia virus 10 (MOV10) protein inhibits retrovirus replication. J Biol Chem 285:14346-55 (2010). WB ; Human . PubMed: 20215113
  • Li X  et al. Identification of sequence features that predict competition potency of siRNAs. Biochem Biophys Res Commun 398:92-7 (2010). WB ; Human . PubMed: 20558136
  • Collino F  et al. Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs. PLoS One 5:e11803 (2010). ICC/IF ; Human . PubMed: 20668554
  • Sakurai K  et al. A role for human Dicer in pre-RISC loading of siRNAs. Nucleic Acids Res : (2010). WB, Purification ; Human . PubMed: 20972213
  • Didiot MC  et al. Cells lacking the fragile X mental retardation protein (FMRP) have normal RISC activity but exhibit altered stress granule assembly. Mol Biol Cell 20:428-37 (2009). PubMed: 19005212
  • Kim HH  et al. HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev 23:1743-8 (2009). IP ; Human . PubMed: 19574298

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