Recombinant
RabMAb

Anti-Argonaute 3 / eIF2C 3 antibody [EPR9576] (ab154844)

Overview

  • Product name
    Anti-Argonaute 3 / eIF2C 3 antibody [EPR9576]
    See all Argonaute 3 / eIF2C 3 primary antibodies
  • Description
    Rabbit monoclonal [EPR9576] to Argonaute 3 / eIF2C 3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human Argonaute 3/ eIF2C 3 (Uniprot: Q9H9G7)

  • Positive control
    • Human fetal brain and fetal kidney lysates.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab154844 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 97 kDa.
  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function
      Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.
    • Sequence similarities
      Belongs to the argonaute family. Ago subfamily.
      Contains 1 PAZ domain.
      Contains 1 Piwi domain.
    • Cellular localization
      Cytoplasm > P-body.
    • Information by UniProt
    • Database links
    • Alternative names
      • 5730550L01Rik antibody
      • Ago 3 antibody
      • Ago3 antibody
      • AGO3_HUMAN antibody
      • argonaute 3 antibody
      • Argonaute3 antibody
      • eIF 2C 3 antibody
      • eIF-2C 3 antibody
      • eIF2C 3 antibody
      • Eif2c3 antibody
      • EIF2C3 protein antibody
      • Eukaryotic translation initiation factor 2C 3 antibody
      • Eukaryotic translation initiation factor 2C3 antibody
      • FLJ12765 antibody
      • hAgo3 antibody
      • MGC86946 antibody
      • Protein argonaute-3 antibody
      see all

    Images

    • All lanes : Anti-Argonaute 3 / eIF2C 3 antibody [EPR9576] (ab154844) at 1/1000 dilution

      Lane 1 : Human fetal brain lysate
      Lane 2 : Human fetal kidney lysate

      Lysates/proteins at 10 µl/ml buffer per lane.

      Predicted band size: 97 kDa

    References

    This product has been referenced in:
    • Voutila J  et al. Development and Mechanism of Small Activating RNA Targeting CEBPA, a Novel Therapeutic in Clinical Trials for Liver Cancer. Mol Ther 25:2705-2714 (2017). Read more (PubMed: 28882451) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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