Anti-ARHGAP22 antibody - C-terminal (ab171320)

Overview

  • Product name
    Anti-ARHGAP22 antibody - C-terminal
    See all ARHGAP22 primary antibodies
  • Description
    Rabbit polyclonal to ARHGAP22 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human ARHGAP22 aa 603-633 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q7Z5H3

  • Positive control
    • MDA-MB231, WiDr and ZR-75-1 cell line lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab171320 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 77 kDa.

Target

  • Function
    Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter.
  • Sequence similarities
    Contains 1 PH domain.
    Contains 1 Rho-GAP domain.
  • Cellular localization
    Cytoplasm. Nucleus. Mainly cytoplasmic. Some fraction is nuclear.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARHGAP22 antibody
    • RHG22_HUMAN antibody
    • Rho GTPase activating protein 2 antibody
    • Rho GTPase activating protein 22 antibody
    • Rho GTPase-activating protein 22 antibody
    • Rho type GTPase activating protein 22 antibody
    • Rho-type GTPase-activating protein 22 antibody
    • RhoGAP2 antibody
    • RhoGap22 antibody
    see all

Images

  • All lanes : Anti-ARHGAP22 antibody - C-terminal (ab171320) at 1/100 dilution

    Lane 1 : MDA-MB231 cell line lysates
    Lane 2 : WiDr cell line lysates
    Lane 3 : ZR-75-1 cell line lysates

    Lysates/proteins at 35 µg per lane.

    Predicted band size: 77 kDa

References

ab171320 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab171320.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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