Overview

  • Product name
  • Description
    Goat polyclonal to ARHGDIG
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog, Baboon
  • Immunogen

    Synthetic peptide:

    EAVPEYRAPGRK

    by a Cysteine residue linker, corresponding to amino acids 43-54 of Human ARHGDIG (NP_001167.2).

  • Positive control
    • HeLa cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab104939 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 25 kDa.

Target

  • Function
    Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.
  • Tissue specificity
    Primarily expressed in pancreas and brain.
  • Sequence similarities
    Belongs to the Rho GDI family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Arhgdig antibody
    • GDIR3_HUMAN antibody
    • OTTHUMP00000067353 antibody
    • OTTHUMP00000194914 antibody
    • Rho GDI 3 antibody
    • Rho GDI gamma antibody
    • Rho GDP dissociation inhibitor (GDI) gamma antibody
    • Rho GDP dissociation inhibitor 3 antibody
    • Rho GDP dissociation inhibitor gamma antibody
    • Rho GDP-dissociation inhibitor 3 antibody
    • Rho-GDI gamma antibody
    • RHOGDI 3 antibody
    • RhoGDI gamma antibody
    • RHOGDI3 antibody
    see all

Images

  • Anti-ARHGDIG antibody (ab104939) at 0.5 µg/ml + HeLa cell lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 25 kDa

References

ab104939 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab104939.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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