Anti-ARHGEF10 antibody (ab117825)

Overview

  • Product nameAnti-ARHGEF10 antibody
    See all ARHGEF10 primary antibodies
  • Description
    Rabbit polyclonal to ARHGEF10
  • Tested applicationsSuitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 950-1000 of Human ARHGEF10 according to O15013.4.

  • Positive control
    • Whole cell lysate from HeLa cells.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: pH: 7-8
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab117825 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
  • Application notesIs unsuitable for WB.
  • Target

    • FunctionMay play a role in developmental myelination of peripheral nerves.
    • Involvement in diseaseDefects in ARHGEF10 are the cause of slowed nerve conduction velocity (SNCV) [MIM:608236]. Affected individuals present a reduction in nerve conduction velocities without any clinical signs of peripheral or central nervous system dysfunction. SNCV inheritance is autosomal dominant.
    • Sequence similaritiesContains 1 DH (DBL-homology) domain.
    • Information by UniProt
    • Database links
    • Alternative names
      • ARHGA_HUMAN antibody
      • ARHGEF10 antibody
      • DKFZp686H0726 antibody
      • GEF10 antibody
      • KIAA0294 antibody
      • MGC131664 antibody
      • Rho guanine nucleotide exchange factor (GEF) 10 antibody
      • Rho guanine nucleotide exchange factor 10 antibody
      see all

    Anti-ARHGEF10 antibody images

    • Detection of Human ARHGEF10 by Immunoprecipitation in whole HeLa cells lysate (1 mg for IP, 20% of IP loaded) using ab117825 at 6 µg/mg of lysate. Subsequent WB detection was done using another Human ARHGEF10 antibody. Detection: Chemiluminescence with exposure time of 3 seconds.

    References for Anti-ARHGEF10 antibody (ab117825)

    ab117825 has not yet been referenced specifically in any publications.

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