Overview

  • Product nameAnti-ARHGEF11 antibody
    See all ARHGEF11 primary antibodies
  • Description
    Mouse monoclonal to ARHGEF11
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: RSESLKGREE MKRSRKAENV PRSRSDVDMD AAAEATRLHQ SASSSTSSLS TRSLENPTPP FTPKMGRRSI ESPSLGFCTD TLLPHLLEDD LGQLSDLEPE , corresponding to amino acids 651-750 of Human ARHGEF11

Properties

Applications

Our Abpromise guarantee covers the use of ab56568 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
    • Tissue specificityUbiquitously expressed.
    • Sequence similaritiesContains 1 DH (DBL-homology) domain.
      Contains 1 PDZ (DHR) domain.
      Contains 1 PH domain.
      Contains 1 RGSL (RGS-like) domain.
    • DomainThe poly-Pro region is essential for plasma membrane localization upon stimulation.
    • Cellular localizationCytoplasm. Membrane. Translocated to the membrane upon stimulation.
    • Information by UniProt
    • Database links
    • Alternative names
      • ARHGB_HUMAN antibody
      • ARHGEF 11 antibody
      • ARHGEF11 antibody
      • DKFZp667F1223 antibody
      • Glutamate transporter EAAT4 associated protein 48 antibody
      • GTRAP 48 antibody
      • GTRAP48 antibody
      • KIAA0380 antibody
      • OTTHUMP00000038716 antibody
      • OTTHUMP00000038717 antibody
      • PDZ RHOGEF antibody
      • PDZ-RhoGEF antibody
      • Rho guanine exchange factor (GEF) 11 antibody
      • Rho guanine nucleotide exchange factor (GEF) 11 antibody
      • Rho guanine nucleotide exchange factor 11 antibody
      • RhoA specific guanine nucleotide exchange factor antibody
      • RhoGEF glutamate transport modulator antibody
      see all

    Anti-ARHGEF11 antibody images

    • Western blot against tagged recombinant protein immunogen using ab56568 ARHGEF11 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-ARHGEF11 antibody (ab56568)

    ab56568 has not yet been referenced specifically in any publications.

    Product Wall

    Application Western blot
    Sample Human Cell lysate - whole cell (human lymphoma cell line)
    Loading amount 120 µg
    Specification human lymphoma cell line
    Gel Running Conditions Reduced Denaturing (10)
    Blocking step Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 30°C
    Username

    Dr. Xiao Qing Lu

    Verified customer

    Submitted Aug 18 2008

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"