Overview

  • Product nameAnti-ARHGEF6 antibody
    See all ARHGEF6 primary antibodies
  • Description
    Rabbit polyclonal to ARHGEF6
  • Tested applicationsSuitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla
  • Immunogen

    Synthetic peptide, corresponding to a region between residues 726 and 776 of Human ARHGEF6 (NP_004831.1).

  • Positive control
    • Jurkat whole cell lysates

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: Tris citrate/phosphate, pH 7-8
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab91572 was affinity purified using an epitope specific to ARHGEF6 immobilized on solid support.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab91572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP
  • Application notesIP: Use at 5-15 µg/mg of lysate.

    Is unsuitable for WB.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionActs as a RAC1 guanine nucleotide exchange factor (GEF).
    • Tissue specificityUbiquitous.
    • Involvement in diseaseDefects in ARHGEF6 are the cause of mental retardation X-linked type 46 (MRX46) [MIM:300436]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
    • Sequence similaritiesContains 1 CH (calponin-homology) domain.
      Contains 1 DH (DBL-homology) domain.
      Contains 1 PH domain.
      Contains 1 SH3 domain.
    • Information by UniProt
    • Database links
    • Alternative names
      • Alpha Pix antibody
      • Alpha-Pix antibody
      • ARHG6_HUMAN antibody
      • ARHGEF6 antibody
      • COOL 2 antibody
      • COOL-2 antibody
      • COOL2 antibody
      • Mental retardation, X linked 46 antibody
      • MRX46 antibody
      • PAK interacting exchange factor alpha antibody
      • PAK-interacting exchange factor alpha antibody
      • PIXA antibody
      • Rac/Cdc42 guanine exchange factor (GEF) 6 antibody
      • Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 antibody
      • Rac/Cdc42 guanine nucleotide exchange factor 6 antibody
      • Rho guanine nucleotide exchange factor 6 antibody
      see all

    Anti-ARHGEF6 antibody images

    • Detection of ARHGEF6 by Western Blot of Immunprecipitate.
      anti-ARHGEF6, at 1 µg/ml, staining ARHGEF6 in Jurkat whole cell lysate immunoprecipitated using ab91572 at 10 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
      Detection: Chemiluminescence with exposure time of 10 seconds.

    References for Anti-ARHGEF6 antibody (ab91572)

    ab91572 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab91572.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"