Overview

  • Product name
  • Description
    Rabbit polyclonal to ARHGEF7
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 218-428 of Human ARHGEF7 (Q14155).

  • Positive control
    • NT2D1, IMR32, U-87 MG and MCF7 whole cell lysates.
  • General notes
    Keep as concentrated solution

Properties

Applications

Our Abpromise guarantee covers the use of ab125870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 90 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Use 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer ( pH8.0).

Target

  • Function
    Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. May function as a positive regulator of apoptosis. May function in cell migration.
  • Sequence similarities
    Contains 1 CH (calponin-homology) domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 SH3 domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARHG7 antibody
    • ARHG7_HUMAN antibody
    • ARHGEF 7 antibody
    • Arhgef7 antibody
    • Beta pix antibody
    • Beta-Pix antibody
    • betaPix antibody
    • betaPix-b antibody
    • betaPix-c antibody
    • Cool antibody
    • COOL-1 antibody
    • COOL1 antibody
    • DKFZp686C12170 antibody
    • DKFZp761K1021 antibody
    • KIAA0142 antibody
    • KIAA0412 antibody
    • mKIAA0142 antibody
    • Nbla10314 antibody
    • P50 antibody
    • P50BP antibody
    • p85 antibody
    • P85COOL1 antibody
    • P85SPR antibody
    • PAK interacting exchange factor beta antibody
    • PAK-interacting exchange factor beta antibody
    • PAK3 antibody
    • Pak3bp antibody
    • PIX antibody
    • PIXB antibody
    • Rho guanine nucleotide exchange factor (GEF) 7 antibody
    • Rho guanine nucleotide exchange factor (GEF) 7b antibody
    • Rho guanine nucleotide exchange factor (GEF7) antibody
    • Rho guanine nucleotide exchange factor 7 antibody
    • SH3 domain containing proline rich protein antibody
    see all

Images

  • Anti-ARHGEF7 antibody (ab125870) at 1/1000 dilution + IMR32 whole cell lysate at 30 µg

    Predicted band size : 90 kDa
  • ab125870, at 1/500, staining ARHGEF7 in paraffin embedded Human AdCA (adenocarcinoma) by Immunohistochemistry.

References

ab125870 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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