Anti-ARID1B antibody (ab84461)
Key features and details
- Rabbit polyclonal to ARID1B
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ARID1B antibody
See all ARID1B primary antibodies -
Description
Rabbit polyclonal to ARID1B -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan -
Immunogen
Synthetic peptide within Human ARID1B aa 1850-1950. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q8NFD5 -
Positive control
- Human Breast Carcinoma, Prostate Carcinoma
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab84461 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Notes |
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Epitope exposure with citrate buffer will enhance staining.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Relevance
ARID1B (AT-rich interactive domain-containing protein 1B) is a component of SWI/SNF chromatin remodeling complexes involved in transcriptional activation and repression of select genes by chromatin remodeling. It binds DNA non-specifically and alters DNA-nucleosome topology. -
Cellular localization
Nuclear -
Database links
- Entrez Gene: 57492 Human
- Omim: 614556 Human
- SwissProt: Q8NFD5 Human
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Alternative names
- 6A3 5 antibody
- ARID 1B antibody
- ARID domain containing protein 1B antibody
see all
Images
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Detection of Human ARID1B by ab84461 at 1:250 dilution using a Formalin-Fixed Paraffin-Embedded section of human breast carcinoma. Detection by means of DAB staining.
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Detection of Human ARID1B by ab84461 at 1:500 dilution using a Formalin-Fixed Paraffin-Embedded section of human prostate carcinoma. Detection by means of DAB staining.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab84461 has been referenced in 1 publication.
- Mashtalir N et al. Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes. Cell 175:1272-1288.e20 (2018). PubMed: 30343899