Overview

  • Product name
    Aripiprazole
  • Description
    Partial dopamine D2 agonist
  • Biological description
    Partial dopamine D2 agonist. Ki (nM) values are 265 (D1), 0.34 (D2), 0.8 (D3), 44 (D4), 1.7 (5-HT1A), 3.4 (5-HT2A), 15 (5-HT2C), 214 (5-HT6), 39 (5-HT7), 57 (α1), 791 (α2), 61 (H1) and >1000 (M1). Antipsychotic and antidepressant activity. Centrally active following oral administration.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Segnitz N  et al. Effects of chronic oral treatment with aripiprazole on the expression of NMDA receptor subunits and binding sites in rat brain. Psychopharmacology (Berl) 217:127-42 (2011). Read more (PubMed: 21484241) »
  • Wang JS  et al. Aripiprazole brain concentration is altered in P-glycoprotein deficient mice. Schizophr Res 110:90-4 (2009). Read more (PubMed: 19239981) »
  • Hirose T & Kikuchi T Aripiprazole, a novel antipsychotic agent: dopamine D2 receptor partial agonist. J Med Invest 52 Suppl:284-90 (2005). Read more (PubMed: 16366516) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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