Overview

  • Product nameAnti-ARK5 antibody
    See all ARK5 primary antibodies
  • Description
    Goat polyclonal to ARK5
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    C-QNRPRPQYLKRYRNR

    , corresponding to internal sequence amino acids 617-631 of Human ARK5 (NP_055655.1)

  • Positive control
    • Human kidney, muscle and ovary lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab92275 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 75 kDa (predicted molecular weight: 75 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInvolved in tolerance to glucose starvation. Phosphorylates ATM. Suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR.
    • Tissue specificityExpressed at high levels in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung and liver.
    • Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
      Contains 1 protein kinase domain.
    • Post-translational
      modifications
      Ubiquitinated with 'Lys-29'- and 'Lys-33'-linked polyubiquitins which appear to impede LKB1-mediated phosphorylation. Deubiquitinated by USP9X.
    • Information by UniProt
    • Database links
    • Alternative names
      • AMP activated protein kinase family member 5 antibody
      • AMPK related protein kinase 5 antibody
      • AMPK-related protein kinase 5 antibody
      • NUAK family SNF1 like kinase antibody
      • NUAK family SNF1-like kinase 1 antibody
      • Nuak1 antibody
      • NUAK1_HUMAN antibody
      • Omphalocele kinase 1 antibody
      • Probable serine/threonine protein kinase KIAA0537 antibody
      see all

    Anti-ARK5 antibody images

    • Anti-ARK5 antibody (ab92275) at 1/0.3 dilution + Human kidney lysate in RIPA buffer at 35 µg

      Predicted band size : 75 kDa
      Observed band size : 75 kDa

    References for Anti-ARK5 antibody (ab92275)

    ab92275 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab92275.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"