Overview

  • Product name
  • Description
    Goat polyclonal to ARK5
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    C-QNRPRPQYLKRYRNR

    , corresponding to internal sequence amino acids 617-631 of Human ARK5 (NP_055655.1)

  • Positive control
    • Human kidney, muscle and ovary lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab92275 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 75 kDa (predicted molecular weight: 75 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Involved in tolerance to glucose starvation. Phosphorylates ATM. Suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR.
    • Tissue specificity
      Expressed at high levels in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung and liver.
    • Sequence similarities
      Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
      Contains 1 protein kinase domain.
    • Post-translational
      modifications
      Ubiquitinated with 'Lys-29'- and 'Lys-33'-linked polyubiquitins which appear to impede LKB1-mediated phosphorylation. Deubiquitinated by USP9X.
    • Information by UniProt
    • Database links
    • Alternative names
      • AMP activated protein kinase family member 5 antibody
      • AMPK related protein kinase 5 antibody
      • AMPK-related protein kinase 5 antibody
      • NUAK family SNF1 like kinase antibody
      • NUAK family SNF1-like kinase 1 antibody
      • Nuak1 antibody
      • NUAK1_HUMAN antibody
      • Omphalocele kinase 1 antibody
      • Probable serine/threonine protein kinase KIAA0537 antibody
      see all

    Images

    • Anti-ARK5 antibody (ab92275) at 1/0.3 dilution + Human kidney lysate in RIPA buffer at 35 µg

      Predicted band size : 75 kDa
      Observed band size : 75 kDa

    References

    ab92275 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab92275.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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