Overview

  • Product name
  • Description
    Rabbit polyclonal to ARL13B
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A recombinant fragment corresponding to a region within amino acids 141 and 428 of Human ARL13B

  • Positive control
    • 293T cell lysate; Mouse liver tissue lysate; Paraffin-embedded U87 xenograft

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab153725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 48 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Involvement in disease
    Defects in ARL13B are the cause of Joubert syndrome type 8 (JBTS8) [MIM:612291]. JBTS is an autosomal recessive disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. Neuroradiologically, it is characterized by cerebellar vermis hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable features include retinal dystrophy and renal disease.
  • Sequence similarities
    Belongs to the small GTPase superfamily. Arf family.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADP ribosylation factor like 13B antibody
    • ADP ribosylation factor like 2 like 1 antibody
    • ADP-ribosylation factor-like protein 13B antibody
    • ADP-ribosylation factor-like protein 2-like 1 antibody
    • AR13B_HUMAN antibody
    • arl13b antibody
    • ARL2-like protein 1 antibody
    • ARL2L1 antibody
    • JBTS8 antibody
    see all

Images

  • Anti-ARL13B antibody (ab153725) at 1/1000 dilution + 293T cell lysate at 30 µg

    Predicted band size: 48 kDa



    10% SDS PAGE
  • Anti-ARL13B antibody (ab153725) at 1/1000 dilution + Mouse liver tissue lysate at 50 µg

    Predicted band size: 48 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded U87 xenograft, labeling ARL13B using ab153725 at 1/500 dilution.

References

ab153725 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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