Overview

  • Product nameAnti-ARMET antibody
    See all ARMET primary antibodies
  • Description
    Rabbit polyclonal to ARMET
  • Tested applicationsSuitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    12 amino acid peptide from near the amino terminus of human MANF.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityPurified IgA
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab67203 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 20 kDa).
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml.

Target

  • FunctionSelectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
  • Sequence similaritiesBelongs to the ARMET family.
  • DomainThe N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
  • Post-translational
    modifications
    May contain sialic acid residues.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Arginine rich mutated in early stage tumors antibody
    • Arginine rich protein antibody
    • Arginine-rich protein antibody
    • ARMET antibody
    • ARMET protein antibody
    • ARP antibody
    • Manf antibody
    • MANF_HUMAN antibody
    • Mesencephalic astrocyte derived neurotrophic factor antibody
    • Mesencephalic astrocyte-derived neurotrophic factor antibody
    • MGC142148 antibody
    • MGC142150 antibody
    • Protein ARMET antibody
    see all

Anti-ARMET antibody images

  • Lane 1 : Anti-ARMET antibody (ab67203) at 1 µg/ml
    Lane 2 : Anti-ARMET antibody (ab67203) at 2 µg/ml

    Lane 1 : rat brain tissue lysate
    Lane 2 : rat brain tissue lysate


    Predicted band size : 20 kDa
  • Ab67203 (2.5 ug/ml) staining of ARMET in human brain tissue by IHC.
  • Immunofluorescence of MANF in Human Brain cells using ab67203 at 20 ug/ml.

References for Anti-ARMET antibody (ab67203)

This product has been referenced in:
  • Di Penta A  et al. A trifluoromethyl analogue of celecoxib exerts beneficial effects in neuroinflammation. PLoS One 8:e83119 (2013). WB ; Mouse . Read more (PubMed: 24349442) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"