Overview

  • Product name
  • Description
    Goat polyclonal to ARMET
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog
  • Immunogen

    Synthetic peptide:

    KFCREARGKENR

    , corresponding to internal sequence amino acids 59-70 of Human ARMET (vNP_006001.2).

  • Positive control
    • Human pancreas lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab77267 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab77267 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution 1/16,000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
    • Sequence similarities
      Belongs to the ARMET family.
    • Domain
      The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
    • Post-translational
      modifications
      May contain sialic acid residues.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • Arginine rich mutated in early stage tumors antibody
      • Arginine rich protein antibody
      • Arginine-rich protein antibody
      • ARMET antibody
      • ARMET protein antibody
      • ARP antibody
      • Manf antibody
      • MANF_HUMAN antibody
      • Mesencephalic astrocyte derived neurotrophic factor antibody
      • Mesencephalic astrocyte-derived neurotrophic factor antibody
      • MGC142148 antibody
      • MGC142150 antibody
      • Protein ARMET antibody
      see all

    Anti-ARMET antibody images

    • Anti-ARMET antibody (ab77267) at 0.3 µg/ml + Human Pancreas lysate (in RIPA buffer) at 35 µg

      Predicted band size : 20 kDa
      Observed band size : 20 kDa

    References for Anti-ARMET antibody (ab77267)

    ab77267 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab77267.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up