Overview

  • Product name
  • Description
    Rabbit polyclonal to ARMETL1
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: TLDLASVDLR KMRVAELKQI LHSWGEECRA CAEKTDYVNL IQELAPKYAA TH, corresponding to internal sequence amino acids 131-182 of Human ARMETL1.

  • Positive control
    • Human liver tissue and tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab122871 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • Function
    Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.
  • Tissue specificity
    Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum.
  • Sequence similarities
    Belongs to the ARMET family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Arginine rich mutated in early stage tumors like 1 antibody
    • ARMET L1 antibody
    • ARMET like protein 1 antibody
    • ARMET-like protein 1 antibody
    • ARMETL 1 antibody
    • CDNF antibody
    • CDNF_HUMAN antibody
    • Cerebral dopamine neurotrophic factor antibody
    • Conserved dopamine neurotrophic factor antibody
    see all

Images

  • ab122871 at 1/20 dilution staining ARMETL1 in paraffin-embedded Human liver tissue by Immunohistochemistry.
  • All lanes : Anti-ARMETL1 antibody (ab122871) at 1/250 dilution

    Lane 1 : RT 4 cell lysate
    Lane 2 : U 251 MG cell lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human liver tissue lysate
    Lane 5 : Human tonsil tissue lysate

    Developed using the ECL technique

References

ab122871 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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