Overview

  • Product nameAnti-ARMS2 antibody
    See all ARMS2 primary antibodies
  • Description
    Rabbit polyclonal to ARMS2
  • Tested applicationsSuitable for: IHC-Fr, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from N terminal of human ARMS2

Properties

Applications

Our Abpromise guarantee covers the use of ab80266 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/50 - 1/500.
WB 1/200 - 1/2000. Predicted molecular weight: 11 kDa.

Target

  • RelevanceARMS2 is thought to play a role in diseases in the elderly. Mutations in this gene have been associated with age-related macular degeneration (ARMD). ARMD is the most common cause of irreversible vision loss. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid (known as drusen) that lie beneath the retinal pigment epithelium and within an elastin containing structure known as Bruch's membrane. ARMD is likely to be a mechanistically heterogeneous group of disorders, and the specific disease mechanisms that underlie the vast majority of cases are currently unknown. However, studies have suggested that both genetic and environmental factors may be implicated.
  • Cellular localizationCytoplasmic
  • Database links
  • Alternative names
    • Age related maculopathy susceptibility 2 antibody
    • Age related maculopathy susceptibility protein 2 mitochondrial antibody
    • ARMD8 antibody
    • ARMS2 age related maculopathy susceptibility 2 antibody
    • ARMS2 antibody
    • LOC387715 antibody
    • Macular degeneration age related 8 antibody
    see all

References for Anti-ARMS2 antibody (ab80266)

ab80266 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. The immunogen for this antibody is within amino acids 1-50 of human ARMS2. Unfortunately, the exact sequence details are proprietary and we are not able to provide any more specific information. I hope this helps, please le...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"