Overview

  • Product name
    Anti-Arp2 antibody [FMS96]
    See all Arp2 primary antibodies
  • Description
    Mouse monoclonal [FMS96] to Arp2
  • Tested applications
    Suitable for: Indirect ELISA, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Dog, Human
  • Immunogen

    Recombinant full length protein (Human)

  • Positive control
    • Total cell extract of C2 mouse myoblast cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab49674 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Indirect ELISA Use at an assay dependent dilution.
ICC/IF Use a concentration of 10 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 40-45 kDa (predicted molecular weight: 45 kDa).

Target

  • Function
    Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament.
  • Sequence similarities
    Belongs to the actin family. ARP2 subfamily.
  • Cellular localization
    Cytoplasm > cytoskeleton. Cell projection.
  • Information by UniProt
  • Database links
  • Alternative names
    • Actin like protein 2 antibody
    • Actin related protein 2 antibody
    • Actin-like protein 2 antibody
    • Actin-related protein 2 antibody
    • ACTR2 antibody
    • ARP2 actin related protein 2 homolog (yeast) antibody
    • ARP2 antibody
    • ARP2/3 COMPLEX antibody
    • ARP2_HUMAN antibody
    • OTTHUMP00000159937 antibody
    • OTTHUMP00000202270 antibody
    see all

Images

  • C2C12 cells were incubated with ab49674 at 10 µg/ml followed by Goat Anti Mouse IgG Alexa-488 (green staining). The red staining is obtained by staining actin with Alexa-546 phalloidin.
  • Immunofluorescence analysis of dendritic cells infected with HIV, staining Arp2 (blue) with ab49674 at 5 mg/ml.

References

This product has been referenced in:

See all 8 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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