Overview

  • Product nameAnti-ARS2 antibody
    See all ARS2 primary antibodies
  • Description
    Mouse polyclonal to ARS2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Partial protein corresponding to amino acids 80 - 876 of human ARS2 (Swissprot id Q9BXP5).

  • Positive control
    • Human pancreas tissue lysate, Jurkat cell lysate and ARS2 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab88392 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 101 kDa.

Target

  • FunctionActs as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.
  • Tissue specificityUbiquitously expressed.
  • Sequence similaritiesBelongs to the ARS2 family.
  • Cellular localizationNucleus > nucleoplasm. Cytoplasm. Predominantly nuclear. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent way.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARS2 protein antibody
    • Arsenate resistance protein ARS2 antibody
    • Arsenite resistance protein 2 antibody
    • Arsenite resistance protein antibody
    • Arsenite-resistance protein 2 antibody
    • ASR2 antibody
    • MGC126427 antibody
    • Serrate antibody
    • Serrate RNA effector molecule antibody
    • Serrate RNA effector molecule homolog (Arabidopsis) antibody
    • Serrate RNA effector molecule homolog antibody
    • SRRT antibody
    • SRRT_HUMAN antibody
    see all

Anti-ARS2 antibody images

  • Anti-ARS2 antibody (ab88392) at 1 µg/ml + human pancreas tissue lysate at 50 µg

    Predicted band size : 101 kDa
    Observed band size : 99 kDa (why is the actual band size different from the predicted?)
  • Anti-ARS2 antibody (ab88392) at 1 µg/ml + Jurkat cell lysate at 50 µg

    Predicted band size : 101 kDa
  • All lanes : Anti-ARS2 antibody (ab88392) at 1 µg/ml

    Lane 1 : ARS2 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 50 µg per lane.


    Predicted band size : 101 kDa
    Observed band size : 101 kDa

References for Anti-ARS2 antibody (ab88392)

ab88392 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab88392.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"