Overview

  • Product name
  • Description
    Goat polyclonal to Artemin
  • Specificity
    ab109812 is expected to recognize all reported isoforms (NP_003967.2; NP_476501.1; NP_476431.2). Reported variants represent identical protein: NP_476431.2, NP_001129687.1 Reported variants represent identical protein: NP_003967.2, NP_476432.2.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Synthetic peptide:

    C-NSTWRTVDRLS

    , corresponding to internal sequence amino acids 202-212 of Human Artemin (NP_003967.2) amino acids 210-220 (NP_476431.2) or amino acids 219-229 (NP_476501.1).

  • Positive control
    • HEK293, HepG2 and Kelly cell lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab109812 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab109812 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 23 kDa.

Target

  • Function
    Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain.
  • Tissue specificity
    Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain.
  • Sequence similarities
    Belongs to the TGF-beta family. GDNF subfamily.
  • Developmental stage
    Expressed during embryogenesis. High level expression seen in fetal kidney and lung while a low level expression seen in the fetal brain.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Artemin antibody
    • Artn antibody
    • ARTN_HUMAN antibody
    • Enovin antibody
    • EVN antibody
    • NBN antibody
    • Neublastin antibody
    • Neurotrophic factor antibody
    see all

Images

  • Anti-Artemin antibody (ab109812) at 0.1 µg/ml + HEK293 lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 23 kDa

References

ab109812 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab109812.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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