Overview

  • Product nameAnti-ARTS1 antibody
    See all ARTS1 primary antibodies
  • Description
    Rabbit polyclonal to ARTS1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, from an internal region of Human ARTS1 (NP_057526.3).

  • Positive control
    • Human liver and prostate tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab118432 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 - 12.5 µg/ml.

Target

  • FunctionAminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesBelongs to the peptidase M1 family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationEndoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • A LAP antibody
    • A-LAP antibody
    • Adipocyte derived leucine aminopeptidase antibody
    • Adipocyte-derived leucine aminopeptidase antibody
    • ALAP antibody
    • Aminopeptidase PILS antibody
    • Aminopeptidase regulator of TNFR1 shedding antibody
    • APPILS antibody
    • ARTS 1 antibody
    • ARTS-1 antibody
    • Arts1 antibody
    • Endoplasmic reticulum aminopeptidase 1 antibody
    • Endoplasmic reticulum aminopeptidase associated with antigen processing antibody
    • ERAAP antibody
    • ERAAP1 antibody
    • ERAP 1 antibody
    • Erap1 antibody
    • ERAP1_HUMAN antibody
    • KIAA0525 antibody
    • kiaa0525 protein antibody
    • PILS AP antibody
    • PILS-AP antibody
    • PILSA antibody
    • PILSAP antibody
    • Puromycin insensitive leucyl specific aminopeptidase antibody
    • Puromycin-insensitive leucyl-specific aminopeptidase antibody
    • Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator antibody
    • type 1 tumor necrosis factor receptors shedding aminopeptidase regulator antibody
    • VEGF-induced aminopeptidase antibody
    see all

Anti-ARTS1 antibody images

  • ab118432 at 12.5ug/ml staining ARTS1 in Formalin-fixed, Paraffin-embedded Human liver tissue by Immunohistochemistry.
  • ab118432 at 12.5ug/ml staining ARTS1 in Formalin-fixed, Paraffin-embedded Human prostate tissue by Immunohistochemistry.

References for Anti-ARTS1 antibody (ab118432)

ab118432 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"