Overview

  • Product nameAnti-ARTS1 antibody
    See all ARTS1 primary antibodies
  • Description
    Mouse monoclonal to ARTS1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 832-942 of Human ARTS1

Properties

Applications

Our Abpromise guarantee covers the use of ab57223 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.
    • Tissue specificityUbiquitous.
    • Sequence similaritiesBelongs to the peptidase M1 family.
    • Post-translational
      modifications
      N-glycosylated.
    • Cellular localizationEndoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • A LAP antibody
      • A-LAP antibody
      • Adipocyte derived leucine aminopeptidase antibody
      • Adipocyte-derived leucine aminopeptidase antibody
      • ALAP antibody
      • Aminopeptidase PILS antibody
      • Aminopeptidase regulator of TNFR1 shedding antibody
      • APPILS antibody
      • ARTS 1 antibody
      • ARTS-1 antibody
      • Arts1 antibody
      • Endoplasmic reticulum aminopeptidase 1 antibody
      • Endoplasmic reticulum aminopeptidase associated with antigen processing antibody
      • ERAAP antibody
      • ERAAP1 antibody
      • ERAP 1 antibody
      • Erap1 antibody
      • ERAP1_HUMAN antibody
      • KIAA0525 antibody
      • kiaa0525 protein antibody
      • PILS AP antibody
      • PILS-AP antibody
      • PILSA antibody
      • PILSAP antibody
      • Puromycin insensitive leucyl specific aminopeptidase antibody
      • Puromycin-insensitive leucyl-specific aminopeptidase antibody
      • Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator antibody
      • type 1 tumor necrosis factor receptors shedding aminopeptidase regulator antibody
      • VEGF-induced aminopeptidase antibody
      see all

    Anti-ARTS1 antibody images



    • Predicted band size : 106 kDa
      ARTS1 antibody (ab57223) at 1ug/lane + A-431 cell lysate at 25ug/lane.

    References for Anti-ARTS1 antibody (ab57223)

    ab57223 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57223.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"