• Product nameAnti-ASAH1 antibody [1A7]
    See all ASAH1 primary antibodies
  • Description
    Mouse monoclonal [1A7] to ASAH1
  • Tested applicationsSuitable for: WB, IHC-P, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 25-125 of Human ASAH1 (NP_808592) with a 26 kDa proprietary tag.

  • Positive control
    • IHC-P: Human heart and prostate tissues WB: ASAH1 transfected 293T cell lysate; recombinant ASAH1 protein


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferpH: 7.40
    Constituent: PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone number1A7
  • IsotypeIgG3
  • Light chain typekappa
  • Research areas


Our Abpromise guarantee covers the use of ab124262 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 45 kDa.
IHC-P Use a concentration of 5 µg/ml.
Sandwich ELISA Use at an assay dependent dilution.


  • FunctionHydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
  • Tissue specificityBroadly expressed with highest expression in heart.
  • Involvement in diseaseDefects in ASAH1 are the cause of Farber lipogranulomatosis (FL) [MIM:228000]; also known as Farber disease (FD). This sphingolipid disease is characterized by subcutaneous lipid-loaded nodules, excruciating pain in the joints and extremities, marked accumulation of ceramide in lysosomes, and death by three years of age.
  • Sequence similaritiesBelongs to the acid ceramidase family.
  • Cellular localizationLysosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • AC antibody
    • ACDase antibody
    • Acid CDase antibody
    • Acid ceramidase antibody
    • Acid ceramidase precursor antibody
    • Acid ceramidase subunit beta antibody
    • Acylsphingosine deacylase antibody
    • ASAH 1 antibody
    • ASAH antibody
    • ASAH1 antibody
    • ASAH1_HUMAN antibody
    • FLJ21558 antibody
    • FLJ22079 antibody
    • N acylsphingosine amidohydrolase (acid ceramidase) 1 antibody
    • N acylsphingosine amidohydrolase 1 antibody
    • N acylsphingosine amidohydrolase antibody
    • N-acylsphingosine amidohydrolase antibody
    • N-acylsphingosine deacylase antibody
    • PHP antibody
    • PHP32 antibody
    • Putative 32 kDa heart protein antibody
    • SMAPME antibody
    see all

Anti-ASAH1 antibody [1A7] images

  • ab124262, at 5 µg/ml, staining ASAH1 in formalin fixed, paraffin embedded Human heart tissue by Imunohistochemistry.
  • ab124262, at 5 µg/ml, staining ASAH1 in formalin fixed, paraffin embedded Human prostate tissue by Imunohistochemistry.
  • All lanes : Anti-ASAH1 antibody [1A7] (ab124262) at 1/500 dilution

    Lane 1 : ASAH1 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Predicted band size : 45 kDa
  • ab124262, detecting recombinant tagged ASAH1 protein by ELISA. Detection limit is approximately 1 ng/ml as a capture antibody.

References for Anti-ASAH1 antibody [1A7] (ab124262)

ab124262 has not yet been referenced specifically in any publications.

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