Overview

  • Product name
    Anti-ASB1 antibody
  • Description
    Rabbit polyclonal to ASB1
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 106-244 of Human ASB1 (Q9Y576).

  • Positive control
    • Human cerebral cortex tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab121198 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May play a role in testis development (By similarity). Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Contains 6 ANK repeats.
    Contains 1 SOCS box domain.
  • Domain
    The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ankyrin repeat and SOCS box protein 1 antibody
    • Ankyrin repeat and SOCS box-containing 1 antibody
    • ASB-1 antibody
    • Asb1 antibody
    • ASB1_HUMAN antibody
    • KIAA1146 antibody
    • MGC11165 antibody
    see all

Anti-ASB1 antibody images

  • ab121198 at 1/25 dilution staining ASB1 in Paraffin-emebedded Human cerebral cortex tissue by Immunohistochemistry.
  • Immunohistochemical staining of Human stomach, lower shows strong cytoplasmic positivity in endocrine cells using ab121198

References for Anti-ASB1 antibody (ab121198)

ab121198 has not yet been referenced specifically in any publications.

Product Wall

Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: TRIS EDTA Buffer pH 9,0
Sample
Human Tissue sections (stomach)
Specification
stomach
Permeabilization
Yes - Wash Buffer from Dako with Tween
Fixative
Paraformaldehyde
Username

Mr. Rudolf Jung

Verified customer

Submitted Apr 01 2015

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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