Overview

  • Product name
  • Description
    Rabbit polyclonal to ASCC3
  • Tested applications
    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: KKFLNEHLQE ACTPELKPVE KTNGSFLWCE VEKYLNSTLK EMTEVPRVED LCCTLYDMLA SIKSGDELQD ELFELLGPEG LELIEKLLQN RI, corresponding to amino acids 197-288 of Human ASCC3.

  • Positive control
    • Human placenta tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122180 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Enhances NF-kappa-B, SRF and AP1 transactivation.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the helicase family.
    Contains 2 helicase ATP-binding domains.
    Contains 2 helicase C-terminal domains.
    Contains 3 SEC63 domains.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activating signal cointegrator 1 complex subunit 3 antibody
    • ASC-1 complex subunit p200 antibody
    • ASC-1 complex subunit p200-KD subunit antibody
    • ASC1p200 antibody
    • ascc3 antibody
    • ATP binding 1 antibody
    • B630009I04Rik antibody
    • dJ121G13.4 antibody
    • DJ467N11.1 antibody
    • HELC1_HUMAN antibody
    • HELIC1 antibody
    • Helicase antibody
    • helicase, ATP binding 1 antibody
    • p200 antibody
    • RNA helicase family antibody
    • RNAH antibody
    • RP1-121G13.4 antibody
    • Trip4 complex subunit p200 antibody
    see all

Images

  • Immunofluorescent staining of Human cell line A-431 shows positivity in plasma membrane and cytoplasm. Recommended concentration of ab122180 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122180 at 1/150 dilution staining ASCC3 in Paraffin-embedded Human Placenta tissue by Immunohistochemistry.

References

ab122180 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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